Where next for antibodies and immunotherapies: understanding the latest innovations
24 May 2022
Advanced Cancer Treatments
Elaine is an expert in explaining detailed science in an accessible and interesting way, making her talks ideal for those without a scientific background. In her talk she’ll tackle two closely linked topics of antibody-based treatments and immunotherapy. She’ll firstly describe progress in antibody-drug conjugates – antibodies that deliver chemotherapy direct to cancer cells. These have come on in leaps and bounds in recent years. Elaine will discuss their key elements – antibody, linker and drug – and the efforts made to improve them. Elaine will also discuss the pick-and-mix approach, describing treatments such as bi-specific T cell engagers and CAR T cells. In these treatments, pieces of antibodies are spliced together with other proteins to activate cancer-fighting T cells. Lastly, no talk on immunotherapy is complete without mention of checkpoint inhibitors. Elaine will look at those we have, and those coming through trials.